We managed perioperative hemostasis for a 72-year-old man with hemophilia A and low inhibitor titers (3 BU/mL), who underwent osteosynthesis for supracondylar fracture of the left humerus.He was treated perioperatively using the combination of high doses of factor VIII (FVIII) with recombinant human Factor VIII Fc fusion protein (rFVIIIFc), VIBRATO
Comments on Triassic pterosaurs with discussion about ontogeny and description of new taxa
Eudimorphodon ranzii was the first Triassic pterosaur to be described and several specimens have been referred to this taxon mainly based on the presence of multicuspid teeth.Since this dental feature has been observed in several other pterosaurs, the revision of some specimens assigned to Eudimorphodon shows that they represent new taxa as follows
Adjunctive Integrated Stress Response Inhibition Accelerates Tuberculosis Clearance in Mice
ABSTRACT Despite numerous advances in tuberculosis (TB) drug development, long treatment durations have led to the emergence of multidrug resistance, which poses a major hurdle to global TB control.Shortening treatment time therefore remains a top priority.Host-directed therapies that promote bacterial clearance and/or lung health may improve the e
Extrinsic apoptotic pathways: A new potential "Target" for more sufficient therapy in a case of cutaneous anaplastic large CD30+ ALK-T--cell lymphoma
The primary cutaneous T-cell lymphomas (CTCL) represent a clonal T-lymphocyte proliferation infiltrating the skin.CD30+ T-cell lymphomas present clinically as nodules with a diameter between 1 and 15 cm, mostly in elderly patients.The role of Rattle Blanket the CD30 molecule in patients suffering from T-cell lymphomas is not completely clear